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Dyskinesia is a condition of abnormal, involuntary, and uncontrollable body movements. Symptoms often start as small tics, tremors, or minor shakes and can progress to head bobbing, body swaying, squirming, flailing, fidgeting, and random movements of hands, lips, tongue, or jaw. This condition can also affect respiratory function and speech.

 

Dyskinesia is very closely associated with Parkinson’s Disease (PD) and presents as a common side effect from the long-term use of levodopa, a pharmaceutical drug used for the management of PD. Long-term and high doses of levodopa significantly increase one’s risk for developing dyskinesia.  Currently, Gocovri™ (amantadine) is the only pharmaceutical approved to treat dyskinesia. Other drugs associated with the onset of dyskinesia include anti-psychotic drugs like haloperidol, thioridazine, and chlorpromazine that are used to treat schizophrenia and bipolar disorder. These drugs work by blocking dopamine.

 

 

 

Side effects from levodopa

  • hypertention
  • hypotension
  • cardiac irregularities
  • syncope
  • gastrointestinal bleeding
  • duodenal ulcers
  • hemolytic and non-hemolytic anemia
  • thrombocytopenia
  • leukopenia
  • delusions
  • hallucinations
  • paranoia
  • insomnia
  • suicidal tendencies
  • convulsions
  • upper respiratory infection
  • urinary tract infections
  • HEART ATTACK (myocardial infarction)

 

 

 

Dopamine is a chemical messenger in the brain that transmits pleasure and satisfaction. It is responsible for overall mood, attention, and helps regulate movement, learning, and emotional responses. When the brain fails to produce enough dopamine, Parkinson’s Disease can result. Dopamine levels can also affect other conditions such as schizophrenia and ADHD.

 

Increasing the level of dopamine naturally consists of solid holistic nutritional fundamentals. Foods high in tyrosine, like peanuts, almonds, pumpkin seeds, sesame seeds, soy, lima beans, lentils, avocados, and bananas can help. Increasing levels of magnesium from foods like almonds, avocado, black beans, brown rice, edamame, cashews, and whole grains are also beneficial for support.  Avoiding foods high in fat, sugar, caffeine, and heavily processed foods should be implemented.  Good quality sleep is imperative to restoring dopamine levels as is decreasing stress. Meditation, breathing practices, massage, and yoga can assist in naturally relieving stress.  Adding the supplements L-Tyrosine and L-theanine additionally support dopamine levels.

 

 

 

How CBD can help

The endocannabinoid system modulates neurotransmitter motor function. CBD is a natural option with low-risk for people suffering from spasticity and involuntary muscle movement. A full-spectrum of cannabinoids synergistically working together produces the most benefit for using this natural medicament. If levels of delta-9-THC are unwanted, defer to a broad spectrum derivative. Methods of CBD delivery include transdermal patches, edibles, smoking, and sub-lingual oils.

 

Transdermal patches can be placed on the skin and last 24 to 48 hours. Edibles such as capsules or gummies can take an hour to take effect and last 6 to 8 hours depending on individual metabolism rates. Oils placed under the tongue are absorbed into the bloodstream, thus producing effects relatively quickly, typically within minutes. Smoking or vaping CBD allows for the medicament to be absorbed instantaneously however the effects wear off quicker. Nasal sprays have the most bio-available uptake of the medicament and can be the fastest-acting.

 

The CBD Continuum carries a variety of products suitable for the natural relief of dyskinesia. We have first-hand experience with immediate dyskenesia relief from our products demonstrated right here in our facility. We can guide you towards products and dosing that may be conducive for each individuals biodiverse needs.

 

 

 

 

 

For more information on dyskenesia and CBD, please visit us at 301 N. Salem Street in downtown Apex.

For more information on holistic nutrition, please visit our parent company SunCodes Nutrition®, LLC.

 

 

 

 

 

Your body is designed to heal 🙂

 

 

 

 

 

 

 

 

 

 

 

References

https://www.ncbi.nlm.nih.gov/pubmed/23714238

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681708/

https://www.mdsabstracts.org/abstract/estimation-of-tardive-dyskinesia-incidence-and-prevalence-in-the-united-states/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958190/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604174/

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/017555s069lbl.pdf

https://www.ncbi.nlm.nih.gov/pubmed/15327040

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394820/

https://www.ncbi.nlm.nih.gov/pubmed/24845114